Research indicates that liposuction can complement the treatment of lymphedema and relieve pain
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Research indicates that liposuction can complement the treatment of lymphedema and relieve pain

A recent study, published in September in the scientific journal The Lancet, suggests that liposuction has the potential to alleviate discomfort in women diagnosed with lymphedema, a chronic condition characterized by disproportionate fat accumulation, mainly concentrated in the legs and occasionally in the arms.

The analysis followed 410 women with the disease over one year. The data revealed that 68% of the participants who underwent surgery reported a decrease of at least two points in pain intensity, using a scale of zero to ten. In contrast, only 8% of women who maintained exclusively conservative clinical treatment showed this reduction.

Clinical Study Conducted in Germany

The results were obtained through a clinical trial conducted in 11 centers located in Germany. Of this group of 410 participants, 278 were operated on with liposuction combined with clinical treatment, while the remaining 132 followed only with conservative management.

Despite these positive findings, specialists warn that it cannot yet be categorically stated that the surgical procedure should be integrated into the treatment protocol. Vascular surgeon Andressa Cristina Sposato Louzada, from Einstein Israelite Hospital, emphasizes that the study marks a significant advance by showing that liposuction can reduce pain and improve quality of life, but stresses that the results must be analyzed considering the risks, the lack of long-term data, and the inherent limitations of the research.

Pain Relief Mechanisms

Louzada explains that the improvement in pain may result from various processes that are not yet fully understood. She details that the affected adipose tissue exhibits structural changes related to inflammation, fibrosis, and alterations in microcirculation. Partial removal of this tissue can decrease pressure on neighboring structures and the mechanical overload of the limbs, thus facilitating movement.

Lymphedema is a chronic illness that primarily affects women and can manifest or worsen during phases of hormonal change, such as puberty, pregnancy, and menopause. In addition to the volumetric increase of the limbs, symptoms include pain, increased sensitivity to touch, a feeling of heaviness, and a propensity to form bruises. The vascular surgeon clarifies that, unlike obesity, where fat is distributed more generally, lymphedema has a specific distribution pattern, often disproportionate to the trunk.

Although some estimates suggest that lymphedema may affect about 10% of women, there is no official population data established to define the true prevalence of the disease. Diagnosis depends on the patient's clinical evaluation and physical examination. Andressa Louzada adds that, although imaging tests can help investigate other associated conditions, there is no single test capable of confirming lymphedema with complete accuracy.

Therapeutic Approaches

The initially recommended treatment is always conservative and must be adapted to each individual. It includes regular physical exercise, nutritional guidance, weight control when necessary, the use of compression stockings, and physiotherapy to optimize mobility and manage associated edema. The doctor observes that lymphatic drainage can help control swelling, but it cannot eliminate the characteristic adipose tissue of the pathology.

Liposuction is not the first therapeutic choice; it is generally considered when the patient experiences persistent pain that does not improve satisfactorily with clinical treatment, or when there are functional limitations that impair locomotion. Louzada reinforces that there is no fixed treatment period applicable to all cases, as the decision is always personalized, considering the symptoms, clinical status, and involved risks.

It is essential to understand that surgery does not constitute a cure for lymphedema. Since the disease is chronic and its mechanisms are not yet fully understood, it cannot be guaranteed that fat removal will permanently interrupt its progression or prevent the emergence of new signs.

Risks and Future Perspectives

Like any surgical intervention, the procedure carries risks. In the study, 47% of the operated patients suffered some adverse event. Possible complications include bruising, fluid accumulation, infections, changes in sensitivity, anemia, and asymmetries in body contour. Among the most serious incidents are deep vein thrombosis, pulmonary embolism, hemorrhages, and lymphatic lesions.

Additionally, the duration of benefits remains uncertain, as the follow-up lasted only 12 months. Therefore, it is necessary to obtain a deeper understanding of the long-term results, identify which patients benefit the most, and verify whether surgery effectively alters the evolution of the disease, the vascular surgeon states. It is concluded that the main advance lies in recognizing that liposuction can be an effective therapeutic alternative for carefully selected patients, and not merely an aesthetic act.

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The U.S. Food and Drug Administration (FDA) has issued a new warning regarding certain medications used to manage diabetes and obesity. Under this warning, the FDA has directed revisions to the safety labeling of GLP-1 drugs such as semaglutide and tirzepatide.

According to the FDA, consuming these drugs may carry a risk of developing a serious eye condition known medically as non-arteritic anterior ischemic optic neuropathy, which is also understood as an eye stroke.

An eye stroke is a condition where the optic nerve of the eye is damaged. The most concerning aspect is that patients often do not feel any pain, and sometimes upon waking up in the morning, there can be slight vision loss in one eye, causing blurred vision.

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A 2024 study published in JAMA Ophthalmology reported a significantly higher risk of non-arteritic anterior ischemic optic neuropathy among users of semaglutide. Based on this research, legal cases have been filed against Novo Nordisk and Eli Lilly in the United States.

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Study indicates that replacing refined grains with whole grains can benefit cardiovascular health
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Study indicates that replacing refined grains with whole grains can benefit cardiovascular health

Swapping processed foods made with refined grains for their whole grain versions can promote improvements in metabolic and cardiovascular health, affecting indicators such as blood pressure, triglycerides, glycemia, and cholesterol. However, a meta-analysis published in September in the European Heart Journal indicated that the effects on body weight and abdominal circumference are modest.

This investigation analyzed 87 clinical trials involving over 6,500 participants, aiming to measure the impact of whole grain consumption on cardiometabolic risk factors. Generally, the benefits became more noticeable when there was a daily intake of 60 to 100 grams of these foods by dry weight (before cooking or hydrating), which corresponds to about four to six servings.

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The meta-analysis revealed that every 48-gram increase in daily whole grain consumption (by dry weight) was associated with an average drop of 0.20 kilograms in body weight and 0.22 centimeters in waist circumference. Reductions were also observed in total cholesterol, LDL, triglycerides, fasting glycemia, and systolic blood pressure.

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Gum disease can lead to kidney problems, doctor explains oral hygiene maintenance methods
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Gum disease can lead to kidney problems, doctor explains oral hygiene maintenance methods

Maintaining oral health is critically important for preventing kidney diseases, despite the apparent illogical nature of this statement. Medical science establishes a link between the condition of the mouth, especially gum health, and kidney health. According to data from the National Kidney Foundation, gum disease can increase the risk of various kidney problems, which has been confirmed in several of the Foundation's studies.

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