In August and September 2478 students from eighteen schools participated in the program, becoming 'scientists for a day.' They worked alongside staff from Merck and partner volunteers from Rhodes University, as well as from the Nelson Mandela Science and Technology Centre in Cariega.
This event was part of the international Curiosity Cube™ tour by the science and technology company, which aims to transform curiosity into scientific careers. The mobile science laboratory Curiosity Cube™ is conducting its second consecutive year in South Africa, and the Eastern Cape is just one of 126 planned stops this year.
Students from various schools in the Eastern Cape underwent three interactive experiments to learn the basics of synthetic biology. This involved using educational gadgets such as Cubelets and magnetic puzzles, allowing them to explore the relationship between enzyme shape and biological processes, the influence of genetic code on traits and behavior, and how gene activation and deactivation enables scientists to create solutions for real-world problems.
All experiments were conducted by Merck staff and volunteers from Rhodes University (Makhanda) and the Nelson Mandela Science and Technology Centre (Cariega), enabling students to interact with scientists working in their own communities and sharing opportunities in STEM.
Jennifer Mohale, Curiosity Cube™ Coordinator at Merck, noted that the experiments demonstrated to the students how concepts of synthetic biology manifest in the real world. She added that these lessons can help shape the future of students by introducing engineering principles and potential careers in life sciences in growing sectors such as medicine or healthcare.
The Curiosity Cube™ initiative aims to awaken interest in STEM careers and remove educational barriers. According to a Merck survey, nearly half (48%) of schoolchildren aged 8 to 13 find it difficult to see themselves as scientists, even if they engage in STEM-related activities daily.
The World Economic Forum indicates that an additional 23 million STEM graduates will be required by 2030 to fill vacancies in these developing fields. To meet this demand, early intervention is necessary: students, especially those aged 8 to 13, need significant experience and relatable role models to envision a future in STEM.
By providing access to STEM education in an engaging and memorable format during a critical period of student life and education, Curiosity Cube™ helps them make this connection, thereby contributing to the development of a strong future workforce in science and technology.
One sixth-grade student shared their impressions after visiting Curiosity Cube™: 'Curiosity Cube™ was a lot of fun, and I learned so much from the scientists. I want to be a natural science teacher when I grow up because you learn so many new things that make you smart, and you can share what you've learned.'
Only in 2025 have 2069 Merck staff volunteers and university partners helped teach 56,035 students worldwide the basics of artificial intelligence using Curiosity Cube™. Previous Curiosity Cube™ tours have also covered topics such as sustainable development, contamination, and the human microbiome.
Curiosity Cube™ is part of Merck's global volunteering program, SPARK™, which celebrates its 10th anniversary this year, and continues the company's Curiosity Labs™ program, where staff conduct practical experiments with students in classrooms.
To date, Merck employees have contributed over 196,800 hours through SPARK™, conducting more than 6,500 events in 48 countries and engaging over 613,400 students.
Besides South Africa, Curiosity Cube™ has visited Botswana, Eswatini, and has newly expanded into Zambia, Lesotho, and Namibia.
In its fifth annual European tour, Curiosity Cube™ will stop in Austria, Belgium, Czech Republic, France, Germany, Ireland, Italy, Netherlands, Spain, Switzerland, and the United Kingdom, and will also visit new locations in Poland, Serbia, and Slovakia.
The lab will also tour the USA and Canada, holding 133 events in cities such as Austin, Boston, Cleveland, Durham, Houston, Kansas City, Milwaukee, New York, San Diego, San Jose, St. Louis, and Toronto.
Since its founding in 2017, over 286,000 visitors from 20 countries in North America, Europe, and South Africa have visited Curiosity Cube™.
Adela Madari, Curiosity Cube™ Coordinator at Merck, stated: 'You can see the confidence of the students growing with each station. They discover that they belong here, and that their ideas matter. Learning science is just the beginning.'
To learn more about upcoming tour stops, visit TheCuriosityCube.com or follow the journey on Instagram using the hashtag @curiositycube_merck. Merck's Life Science business operates through MilliporeSigma in the United States and Canada.