Experts discuss rules for choosing a pathology laboratory and the importance of personalized testing
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Experts discuss rules for choosing a pathology laboratory and the importance of personalized testing

In the modern world, where preventive medicine extends far beyond standard blood tests to include genetic testing, advanced imaging, and artificial intelligence (AI), people often fall into misconceptions. Many are influenced by attractive advertising and undergo test packages that they do not actually need.

Three renowned specialists participated in a session at the Health Wealth Summit: Dr. Navin Dang, founder and director of Dr. Dang's Lab; Dr. Harsh Mahajan, Managing Director of Mahajan Imaging; and Dr. Arvind Lal, Executive Chairman of Lal PathLabs. These experts openly shared their views on the nuances of preventive medicine, selecting correct diagnostic tests, and personalized health screening.

Dr. Navin Dang emphasized that accurate diagnosis is the foundation of any proper treatment. He advised against choosing a laboratory solely based on low prices or tempting packages. When making a choice, one should pay attention to the presence of qualified doctors, such as pathologists and microbiologists, the lab's accreditation, and the possibility of receiving medical consultation regarding the results.

He warned that the slightest error at the diagnostic level can completely distort the direction of patient treatment, so correct identification is of paramount importance.

Dr. Harsh Mahajan explained that there are two types of medical tests: 'preventive screening' for asymptomatic individuals and 'diagnostic testing' for those who are ill. He cautioned against falling for packages named 'Silver,' 'Gold,' or 'Platinum.' Often, the number of tests in advertisements is artificially inflated by counting individual components of a single analysis.

According to Dr. Mahajan, the needs of a 20-year-old young person differ from those of a 40- or 50-year-old person. Therefore, the selection of tests must be based on age, family history, and chronic diseases. He noted that testing is necessary, but its correctness and relevance are more critical.

Dr. Arvind Lal stated that one cannot consider oneself healthy based only on appearance or feeling well. Diseases such as diabetes and high blood pressure can remain unnoticed for a long time. He recommended regularly checking blood sugar levels, cholesterol, blood pressure, and kidney function, especially for those with similar ailments in their family.

Speaking about nutrition, he advised avoiding excessive amounts of sugar, salt, fried food, vegetable fats, and excess ghee. He also insisted on a daily walk of 30–45 minutes. Dr. Lal humorously noted that the cost of a thyroid test is now even lower than a cinema ticket, so necessary checks should not be postponed due to financial considerations.

Dr. Navin Dang reported that diagnostic testing is moving towards predictive medicine. HbA1c and HOMA-IR tests are very useful for determining the state of insulin resistance and diabetes. Additionally, tTG tests are conducted to assess gut microbiome and celiac disease.

Dr. Harsh Mahajan added that if there is a family history of cancer, genetic testing and full-body MRI can help identify early risks. However, proper consultation is extremely necessary before such examinations. Dr. Lal cited the example of Angelina Jolie, who underwent preventive surgery after identifying a genetic risk for the BRCA1 mutation, clarifying that having a genetic risk does not guarantee the development of the disease.

Dr. Lal noted that a serological test conducted in rural areas for typhoid diagnosis may yield a negative result in early stages, so it cannot be considered a substitute for a blood culture. Dr. Navin Dang warned that incorrect and unnecessary testing leads to the uncontrolled use of antibiotics, which increases the risk of antimicrobial resistance (AMR), when drugs stop working in the body.

In conclusion, Dr. Mahajan clarified the difference between general AI, such as ChatGPT, and medical AI. While general AI can help understand medical terms, relying on it for diagnosis or treatment is strictly forbidden. Medical AI systems (such as Carpel.ai) can speed up, increase accuracy, and eliminate reporting errors, assisting doctors, but they can never replace a qualified specialist.

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Experts Discuss Rise in Youth Heart Disease and Women's Pregnancy Issues: The Role of Lifestyle and COVID-19

Despite several years having passed since the COVID-19 pandemic, the question often arises whether a sudden illness or heart attack in a young person is a consequence of coronavirus. At the Health Wealth Summit forum, specialists held an open discussion on this serious topic.

Leading doctors from the country participated in the session: Senior Cardiologist Dr. Padmashri D.S. Gambhir, Dr. Manoj Kumar, Dr. Sanjay Sachdeva, and Gynecologist Dr. Priti Agrawal. They thoroughly discussed the true causes of the increase in heart disease among youth, stress, and fertility problems in women.

Dr. Padmashri D.S. Gambhir emphasized that while the COVID-19 pandemic had a negative impact on the blood clotting system and organs, contributing to the rise in heart disease cases, it is incorrect to blame the coronavirus exclusively. He presented statistics showing that less than half of young patients with a heart attack had ever had COVID-19, whereas over 70% of such patients had never encountered the infection. This indicates that lifestyle changes and other medical factors play an equally significant role.

Dr. Manoj Kumar reported that a study conducted in the UK showed an increased risk of heart attack in people who recovered from COVID-19 because the virus affects the inner lining of blood vessels. However, besides this, other significant 'unconventional risk factors' are rapidly emerging. One of these is a sedentary lifestyle: the risk of a heart attack doubles for people who spend more than ten hours a day sitting. Dr. Sanjay Sachdeva added that factors such as high blood pressure, diabetes, smoking, and obesity are causing problems in young people at a very early age. Furthermore, weakened immunity and nasal and sinus hygiene issues make the body more susceptible to other infections.

Dr. Gambhir explained that mental stress and our work style directly determine health status. He highlighted 'Type A Personality'—people who constantly experience anxiety, participate in competitive races, and take everything to heart; these individuals are at the highest risk of heart attack. Conversely, people with 'Type B Personality,' who remain calm about work and leave office worries at home, remain safer. Doctors advise developing a 'Developed India,' but without immersing oneself in the 'stress furnace' or bringing office stress home.

Discussing reproductive health, Dr. Priti Agrawal noted that during COVID-19, many couples postponed family planning. Naturally, the quality and quantity of eggs in women decrease with age. Women who decided to conceive after the age of 30–35 faced difficulties. Additionally, the growing prevalence of smoking, alcohol consumption, and excessive stress among modern youth negatively affects their reproductive health. Therefore, instead of blaming only COVID-19, it is much more important to seek medical consultation in a timely manner.

The general message from the experts was that changing lifestyles, fast food, lack of physical exercise, and excessive psychological stress have become the main enemies of health. If diet and daily routine are adjusted in time, the probability of developing heart disease and other serious problems can be significantly reduced.

Experts recommend cholesterol checks for people over 35 to prevent heart disease
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Experts recommend cholesterol checks for people over 35 to prevent heart disease

In recent years, there has been a significant increase in the number of heart diseases. To prevent their development, doctors advise undergoing cholesterol level testing, especially for individuals who have reached the age of 35. According to data from the American Heart Association and NHLBI, some people have an increased risk of developing heart diseases. Since high cholesterol is one of the risk factors for heart disease, timely checking of this indicator is necessary to protect against the risk of a heart attack.

Dr. Tarun Kumar from the Cardiology Department of Mulchand Hospital in Delhi emphasized the critical importance of maintaining normal cholesterol levels in the body, as this helps protect against numerous cardiac pathologies. Although there are other causes of heart disease, cholesterol control remains indispensable. Given the increase in morbidity, conducting appropriate tests has become a vital step for prevention. For determining cholesterol levels, people over 35 are recommended to undergo a lipid profile test, but this check should also be done by other population groups.

Cholesterol testing is recommended for those who are overweight, suffer from diabetes, have high blood pressure or kidney diseases, as well as those with a family history of heart disease. Additionally, people who smoke and drink alcohol should also undergo this check.

The total cholesterol level in the body should be less than 200 mg/dL. A range from 200 to 239 mg/dL is considered borderline, and a level of 240 mg/dL and above is classified as elevated total cholesterol. It is also important that LDL levels are below 100 mg/dL, and HDL levels exceed 40 mg/dL.

To control cholesterol levels, it is recommended to exercise daily for half an hour. It is necessary to avoid excessive consumption of fried food and fast food, as well as limiting the intake of large amounts of oil.

Experts recommend taking the Lp(a) test to assess heart health, as lipoprotein levels are important for preventing heart attacks
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Experts recommend taking the Lp(a) test to assess heart health, as lipoprotein levels are important for preventing heart attacks

Even if cholesterol levels in the body are within the normal range, this does not guarantee the absence of heart disease or the risk of a heart attack. Doctors emphasize that the state of the heart cannot be assessed based on a single blood test. The level of Lp(a) must also be taken into account.

Professor Dr. Tarun Kumar from the Cardiology Department of Mulchand Hospital explained that the arteries supplying blood to the heart are called coronary arteries. When cholesterol accumulates on the inner wall of these arteries, plaque forms. Sometimes the top layer of this plaque can rupture, leading to the formation of a thrombus. This thrombus can obstruct blood flow to the heart and cause a heart attack, even when cholesterol levels are normal.

The risk of a heart attack depends not only on the overall cholesterol level; Lp(a) can also increase this danger. This indicator is called lipoprotein(a) and is largely determined by genetics. Although most people undergo a lipid profile test, they often skip the Lp(a) check because it is not included in the standard analysis, and a separate blood test is required to determine this indicator.

There is a risk of a heart attack if the Lp(a) level reaches or exceeds 125 nmol/L or 50 mg/dL. Everyone is recommended to take the Lp(a) test at least once. If an elevated level is detected, treatment should be undertaken according to a doctor's recommendation to reduce the threat of a heart attack. Nevertheless, it is extremely important to maintain normal cholesterol levels, lead a healthy lifestyle, avoid smoking and alcohol consumption, and control stress levels.

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