Democratic Alliance demands parliamentary inquiry into shortage of up to 50 essential medicines in South Africa
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IOL
iol.co.za

Democratic Alliance demands parliamentary inquiry into shortage of up to 50 essential medicines in South Africa

The Democratic Alliance (DA) has expressed serious concern over the shortage of up to fifty critical medications within South Africa's public healthcare system. The party warns that patients may face adverse reactions to substitute drugs or cease treatment altogether.

The DA insists that the parliamentary Health Committee investigate the causes and scale of these shortages, as well as examine the measures being taken to protect patients.

DA's health representative, Michelle Clark, stated that she has requested a special committee meeting and demanded the attendance of Minister of Health Aaron Motsoaledi, the Department of Health, the South African Health Products Regulatory Authority (SAHPRA), the company Pharmaceuticals Made In South Africa (Pharmisa), and the South African Pharmaceutical College before this committee.

The list of drugs highlighted by the DA includes amlodipine, used for controlling high blood pressure and preventing angina; rosuvastatin, used to lower cholesterol levels and reduce the risk of heart attacks and strokes; and metformin for managing type 2 diabetes.

The list also included olanzapine, intended for treating schizophrenia and bipolar disorder, especially manic episodes; pregabalin, used in the treatment of nerve pain, seizures, and anxiety disorders; and mebendazole, which combats intestinal helminths.

Clark warned that patients could be at risk if they have to switch to alternative medications. She emphasized: 'There is a significant risk that some patients may experience adverse reactions to substitute medicines, and the overall risk that deeply concerns the DA is that some patients might fear substitute drugs or become confused by them and subsequently stop treatment.'

Disruptions in medicine supply have also been reported in the provinces of Gauteng and the Western Cape. In Gauteng, the shortage in public hospitals and clinics is linked to supplier delays, procurement timelines, changes in drug contracts, and general pressure on supply chains. The provincial department of health reported that it is moving existing stocks between facilities, purchasing medicines from alternative approved suppliers, and providing clinically appropriate substitutes where necessary.

In the Western Cape, provincial health authorities have called for national intervention due to persistent medicine shortages. Stated problems include production and regulatory complexities, import and customs delays, as well as delays in drug testing and release.

The DA reported receiving information that some local pharmaceutical manufacturers are blaming new SAHPRA regulations and the Single Exit Price (SEP) for the decline in local production. Clark stated: 'The DA has reports that some local drug manufacturers blame new SAHPRA regulations and the Single Exit Price (SEP) for the decline in the local pharmaceutical industry, which affects medicine availability. Parliament must investigate this so we can end the medicine shortage.'

The SEP is a regulated price at which manufacturers and importers sell medicines in the private sector of South Africa; however, it does not apply to medicines supplied to the state.

The DA demands that the Health Committee receive a comprehensive briefing on the causes of the shortage, its impact on patients, the list of unavailable medicines, and the measures implemented to mitigate health risks. Clark concluded: 'The DA believes that South Africans who rely on the public health system for critical and chronic medications should be able to count on it without exception.'

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South African Ministry of Health seeks alternative medicines due to shortage of critical drugs
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South African Ministry of Health seeks alternative medicines due to shortage of critical drugs

The National Department of Health in South Africa has confirmed that it is actively searching for and procuring alternative medicines amid the scarcity of vital medications.

A representative from the National Department of Health, Foster Mohale, told the publication IOL that the current supply issues are caused by a combination of factors. These include geopolitical tensions in the Middle East, as well as instances of non-compliance with regulatory requirements by local manufacturers under the South African Health Products Regulatory Authority (SAHPRA).

Mohale stated that the Department is engaging with suppliers and acquiring alternative medicines from other sources to minimize the negative impact on patients. He added that until supply restrictions are lifted, some patients may temporarily switch to clinically appropriate substitute drugs for treating the same conditions.

He also emphasized that the Department will closely monitor the situation's development and work with all stakeholders to restore normal supply levels as soon as possible.

The Democratic Alliance (DA) has also expressed concern over the shortage of up to fifty critical medicines. The party warned that patients might experience adverse reactions to substitute drugs or completely stop treatment.

The DA strongly urged the parliamentary Health Committee to investigate the scale of the shortage, its causes, and the measures being taken to protect patients. DA's health spokesperson, Michelle Clark, said she has requested the convening of a special committee and insists that the Minister of Health Aaron Motsoaledi, the Department of Health, SAHPRA, Pharmisa, and the South African Pharmaceutical College appear before this committee.

Clark noted the potential risks to patients when switching to alternative medication. She stressed that there is a significant risk of adverse reactions to substitute drugs, as well as a general risk that greatly concerns the DA—patient fear or confusion regarding the substitution, which could lead them to discontinue treatment.

Among the mentioned medications are amlodipine, used to control high blood pressure and prevent angina; rosuvastatin, which treats high cholesterol and reduces the risk of heart attacks and strokes; and metformin, used to manage type 2 diabetes. The list also includes olanzapine for treating schizophrenia and bipolar disorder, especially manic episodes; pregabalin for relieving nerve pain, seizures, and anxiety disorders; and mebendazole, which is used against intestinal parasitic infections.

How to prepare the SUS to ensure the continuity of oncological care during health and environmental crises
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How to prepare the SUS to ensure the continuity of oncological care during health and environmental crises

The interruption or postponement of medical appointments due to events such as pandemics or floods can have serious consequences for individuals with cancer, who depend on rapid diagnosis, constant treatment, and specialized monitoring. Maintaining oncological care during emergencies is not just a matter of service organization, but a vital priority to save lives and reduce social disparities.

In Brazil, this challenge is aggravated by the high incidence of the disease, with cancer being the second leading cause of mortality in the country. Projections from the International Agency for Research on Cancer (IARC) indicate a potential increase of 84% in annual cases between 2022 and 2050.

Cancer in extreme situations

This scenario requires more than just expanding prevention, diagnosis, and treatment capacity; it requires preparing the healthcare system itself to operate continuously in the face of increasingly frequent and interconnected crises. Notable examples, such as the Covid-19 pandemic and the floods in Rio Grande do Sul in 2024, demonstrated how distinct emergencies can harm healthcare assistance.

During times of crisis, procedures and appointments may be suspended, health units may lose functionality, and patients may face problems with mobility and access to medication and clinical follow-up. The impacts are more severe for those who already face social, territorial, and economic barriers.

The Brazilian experience shows that crisis preparedness must explicitly include cancer control. Although the Unified Health System (SUS) ensures universal and free access, obstacles related to financing, regional differences, and coordination between services persist.

Resilience, in this context, means the ability to anticipate risks, absorb shocks, adjust service organization, and learn from mitigation tactics used. This implies not only restoring hospitals after an emergency but preserving all phases of the oncological journey, from prevention and diagnosis to palliative care.

This vision was discussed in a national workshop held in Rio de Janeiro in December 2025. The event was organized by IARC, the Pan American Health Organization (PAHO), and the National Cancer Institute (INCA), bringing together experts in public policy, health professionals, researchers, and civil society representatives. The focus was on defining action priorities, based on the experiences of Covid-19 and the floods in Rio Grande do Sul. The discussions culminated in a scientific article published in the journal The Lancet Regional Health – Americas.

The article highlighted that strengthening resilience requires coordinated actions on four fronts: governance, service delivery, resources, and financing. The lack of reliable data, for example, prevents the location of patients with interrupted treatment. Without coordination among managers, referral to other services becomes more complex, and lack of funds can delay the response.

Five priorities to strengthen cancer control in Brazil and the SUS

The first priority is to integrate oncological care into emergency response and preparedness plans. Contingency plans must specify which services must remain active, how to restructure care flows, and how to ensure the continuity of vital treatments. It is crucial that there is an agreement between the Union, states, and municipalities so that these measures can be applied in various locations.

The second goal is to improve and unify health information systems, which are currently dispersed. Data that can be exchanged between systems helps identify patients with pending exams or appointments, monitoring interruptions and reallocating demand among units. It is equally necessary to ensure that managers and professionals have access to the necessary information to decide, while maintaining the security of personal data.

The third priority involves protecting infrastructure and the workforce. Hospitals, radiotherapy services, laboratories, transport networks, and supply systems must be included in contingency plans. It is also necessary to train professionals to act in exceptional circumstances, providing clear protocols, support teams, and communication channels that facilitate the reorganization of care.

The fourth priority is to plan the resumption of care with a focus on equality. Reactivating services based only on operational capacity, ignoring clinical and social needs, can accentuate existing inequalities. Patients with higher clinical risk, paralyzed treatments, and access difficulties must be identified and prioritized, with support from primary care.

Finally, it is imperative to establish flexible financing mechanisms for emergencies. The ability to mobilize funds quickly, rebuild damaged structures, and temporarily increase service offerings defines the speed of recovery. Clarity on financing and pre-defining responsibilities help prevent the response from depending solely on improvised solutions.

Preparing the system to protect lives

These guidelines do not imply creating a system parallel to the SUS. On the contrary, they point to the need to reinforce existing mechanisms, improve regional articulation, and incorporate resilience into routine health planning. The experience gained in primary care, care networks, and national cancer control policies provides a solid foundation for progress.

However, effective implementation depends on firm commitments: well-defined institutional responsibilities, sufficient resources, indicators of care continuity, and evaluation methods capable of converting the lessons of each crisis into lasting improvements. The participation of patients and civil society entities is fundamental to discovering barriers that administrative metrics may not reveal.

Considering the projected growth in cancer cases and the possibility of simultaneous crises occurring, the issue transcends the simple expansion of care under normal conditions; it is about preventing emergencies from interrupting access to oncological diagnosis and treatment. Strengthening the resilience of cancer control means understanding that care must be planned before the crisis, protected during it, and improved in the recovery phase.

Thus, it is believed that this situation represents an opportunity to reaffirm the SUS's commitment to universality and equity. A system ready to face adversity not only handles emergencies better but also enhances its capacity to provide dignified, coordinated, and timely care to the population.

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