American researchers have developed the most extensive atlas to date of single-cell transcriptomes of the dorsolateral prefrontal cortex of the human brain, covering various stages of human life.
As part of the same scientific initiative, colleagues of the scientists studied the characteristics of the brain transcriptome in people suffering from diseases such as Alzheimer's disease, Parkinson's, schizophrenia, and bipolar disorder.
The results of these studies, published in the journal Nature, may contribute to the discovery of new targets for the development of drugs intended for the therapy of these pathologies.