Researchers from the University of Florida in Jacksonville, including Erin Mobley, presented long-term monitoring data of children who underwent chemotherapy treatment using doxorubicin. The study compared groups of children who were administered the cardioprotector dexrazoxane and those who received treatment without it.
It was found that the use of this cardioprotector led to a significantly lower incidence of left ventricular dysfunction. The analysis included 895 participants in pediatric oncology clinical trials.
The average dose of doxorubicin received by patients was 360 milligrams per square meter of body surface area. Furthermore, 51% of patients received a bolus intravenous injection of dexrazoxane at ten times the dose before starting the drug administration.
Dynamic echocardiogram studies were conducted for all participants, totaling 2279. The average follow-up period was 5.9 years; 230 participants were monitored for at least 10 years, and nearly 200 for at least 15 years. The results of this work were published in the Journal of Clinical Oncology.
Patches intended for pimple treatment have gained great popularity in both pharmacies and social media, presenting various variations in colors and shapes. However, the question arises whether these items truly help combat acne.
The effectiveness of these products is directly linked to the type of lesion. The most common patches, made with hydrocolloid, have the ability to accelerate healing and reduce inflammatory signs of certain pimples, although they cannot replace complete dermatological treatment nor work in all situations.
According to dermatologist Glauce Eiko from the Brazilian Society of Dermatology (SBD), these patches work by absorbing the secretion of the pimple and maintaining a moist and controlled environment, which is ideal for healing. They act as a physical barrier, preventing the lesion from coming into contact with friction, manipulation, or contamination, which could result in secondary infections and scarring.
The indication and success level of the patch change according to the stage of the pimple's development. The best performance is observed when the lesion already has a pustule with a white head. In this scenario, hydrocolloid is highly effective at actively sucking out pus and exudate, resulting in reduced swelling, volume, and redness.
Patches are also recommended when the pimple has already ruptured, functioning as a dressing that protects the area from dirt and ultraviolet radiation, preserving the skin's natural moisture and promoting healing.
In early stages of inflammation, characterized only by a sensitive papule without a white head, the benefit is smaller, restricted mainly to the function of a barrier against manipulating the lesion. For internal pimples, such as deep nodules and cysts, as well as for comedones (open or closed blackheads), patches offer no advantages.
There are also patches that incorporate active substances such as salicylic acid, niacinamide, and microneedles; the latter being small soluble structures that release components directly into the lesion. However, dermatologist Barbara Miguel from Einstein Israelite Hospital points out that scientific evidence regarding the extra benefit of these substances is still limited.
To ensure safety, it is essential to purchase only products registered by the National Health Surveillance Agency (Anvisa). Good application practices include ensuring that the skin is clean and completely dry, avoiding the application of creams, serums, or oils on the pimple, as these decrease the material's adhesion.
The patch must cover the lesion entirely and be gently pressed for ten to twenty seconds to ensure proper fixation. The ideal duration of wear is between six and twenty-four hours, or until the hydrocolloid becomes opaque and whitish, indicating maximum secretion absorption.
Users of retinoids or benzoyl peroxide should be cautious when applying these products under the patch. If they are part of the routine, acids should only be applied to the areas adjacent to the lesion, as the occlusion generated by the patch can intensify the penetration of substances and cause severe irritation. When removing the patch, the guidance is to do so slowly along the edges and lightly moisturize the area to aid in restoring the skin barrier.
Barbara Miguel emphasizes that none of these procedures replaces the advice of a dermatologist, warning that such products do not treat the origin of acne. People with moderate to severe or recurrent acne need specialized evaluation to treat the inflammatory process and prevent scars.
Singapore is employing an unusual strategy to combat dengue fever by releasing ten million mosquitoes every week. These insects are not ordinary; they are specially bred male mosquitoes of the Aedes genus carrying the naturally occurring Wolbachia bacterium.
When these males mate with wild females, their eggs do not hatch, which helps reduce the mosquito population. This approach aims not just to eliminate insects but to use biological methods to disrupt their reproduction and decrease disease transmission.
This strategy is already showing promising results. In some areas of Singapore, the Aedes mosquito population has decreased by 90%, and a recent trial showed about 71% protection against dengue infection.
In the context of the situation in India, where 2.33 lakh cases of dengue were registered in 2024, the question arises about the possibility of applying this unconventional tactic to solve the dengue problem in India.
During the first six months of this year, 27 individuals were identified in Qatar who submitted fraudulent experience certificates to obtain a license in the healthcare sector. These individuals are permanently barred from working in the country's healthcare sector.
Dr. Saad Al Kaabi, Director of Professions in Healthcare (DHP) at the Ministry of Public Health, stated that qualification data is verified during the initial stages of registration and licensing. This preliminary screening helps detect fraudulent applications early on.
The Ministry of Public Health emphasized its commitment to maintaining the highest standards in licensing international medical professionals, ensuring that only highly qualified specialists are authorized to provide safe and quality medical services in Qatar. This verification process is conducted in collaboration with specialized institutions to confirm the authenticity of the information provided.
Furthermore, the country recently centralized its healthcare system, meaning residents no longer need a medical record to receive medical care. Their medical number will now be accessible alongside their Qatar ID (QID). This decision was made by the Minister of Public Health, Mansour bin Ibrahim Al Mahmoud, in April of this year.
