The U.S. Food and Drug Administration (FDA) has granted approval for the first preventive influenza vaccine based on mRNA. This was announced in an official press release from the pharmaceutical company Moderna.
The drug is named mRNA-1010 (mFLUSIVA). Its composition includes mRNA of surface hemagglutinins from three different influenza virus strains: A/H1N1, A/H3N2, and B/Victoria. Each strain contains 12.5 micrograms of antigen.
One of the key advantages of this vaccine is the ability to promptly modify its antigenic composition in accordance with current seasonal recommendations provided by the World Health Organization. This drug is intended to prevent influenza infection in individuals over 50 years of age.
As part of the statewide campaign 'Clean Diet – Strike Against Counterfeits,' led by Rajasthan Chief Minister Bhajanlal Sharma and Health Minister Gajendra Singh Khinvasara, the Department of Food Safety and Drugs is actively working against unsafe and counterfeit food products. During such activities, approximately 1600 kilograms of Sona Papdi were destroyed in Jaipur.
A team of food safety specialists from the headquarters in Jaipur conducted an inspection of the production unit of 'M/s Anand Dhabas' Sona Papdi, under the direction of Food Safety Director Dr. T. Shubhamganla, and under the supervision of Additional Commissioner Bhagwat Singh and Joint Commissioner Dr. Vijay Prakash Sharma.
The department director stated that numerous deficiencies regarding sanitary norms and food safety standards were identified at the enterprise during the inspection. Team members collected samples of Sona Papdi and almond slices for laboratory analysis.
Upon inspection, it was found that a large quantity of finished Sona Papdi lacked packaging date and expiry date labeling. Considering the serious violation of mandatory food product labeling regulations, the decision was made to destroy approximately 1600 kilograms of the available Sona Papdi.
The enterprise is also being sent a separate notice for improvement regarding other deficiencies found during the inspection. Both samples collected by the food safety officers will be sent to the state food laboratory for testing. Necessary legal action will be taken according to the provisions of the Food Standards and Safety Act after receiving the test results.
Additional Commissioner Bhagwat Singh emphasized that the state government is committed to providing the public with clean, safe, and quality food products. Under the 'Clean Diet – Strike Against Counterfeits' campaign, strict measures continue against counterfeiting, unsafe ingredients, and violations of food safety standards. The production and sale of food products without established labeling and adherence to food safety standards are unacceptable under any circumstances.
The Food Safety Department appealed to the public to use only reliable, standard-quality food products and to immediately report any complaints regarding counterfeiting, suspicious quality, or violations of food safety standards to the department.
Pens used in obesity treatment have become common, but the cost of these medications prevents many Brazilian citizens from accessing them. According to Deutsche Welle (DW), this financial barrier particularly affects lower-income populations, who ironically are the ones suffering most from the disease.
Patients who cannot maintain treatment risk abandoning it or resorting to illegal products. Currently, no weight loss medication is available in the Unified Health System (SUS).
Recent data from Vigitel, provided by the Ministry of Health, indicates that 25.7% of adults in Brazil struggle with obesity. This condition can trigger other serious complications, such as diabetes, cancer, and cardiovascular problems.
The most modern drugs demonstrate superior efficacy compared to older methods. While previous treatments resulted in a loss of 5% to 10% of body weight, medications that mimic GLP-1 action, such as Wegovy and Ozempic, can promote a reduction of up to 17%. With tirzepatide, the active ingredient in Mounjaro, this index can reach 22%.
However, access remains restricted. A survey conducted by NielsenIQ Brazil revealed that the pens are present in approximately 5% of Brazilian households, and in 84% of these homes, the medications generate a high or moderate financial impact on the monthly budget.
For endocrinologist Paulo Miranda, coordinator of the International Department of the Brazilian Society of Endocrinology and Metabolism (SEBM), the disparity in access represents a global issue. He emphasizes the need for these medications to be included at an affordable cost for the public who would benefit from these treatments.
The reduction of semaglutide patents allowed new manufacturers to enter the market and contributed to price decreases. In June, the first national pen with this active ingredient, Ozivy, manufactured by EMS, was launched in retail. Furthermore, five other semaglutide-based medications obtained approval from Anvisa.
The Ministry of Health assures that increased competition should result in a significant drop in prices. Experts point to possible reductions of up to R$ 1 thousand per month in certain treatments.
However, tirzepatide remains more expensive. Treatments with Mounjaro cost between R$ 1,500 and R$ 3,000 monthly. Rachel Teixeira, an endocrinologist, warns that if the cost is prohibitive, it is better not to start the treatment, as suspension tends to cause weight to return to the initial level. She also warns that managing obesity should not be seen merely as a temporary expense.
Obesity control requires more than just medication; nutritional counseling and physical exercise are also part of the therapeutic plan and can increase total costs. Bruno Gualano, president of the Center for Lifestyle Medicine at the Faculty of Medicine of the University of São Paulo (USP), points out that access to a healthy lifestyle is also unequal.
Due to the lack of resources for continuous treatment, some people end up buying pens of illicit origin. Anvisa condemns this practice, as there is no guarantee regarding the origin, purity, transport, or storage of these items.
It is concluded that, according to experts, expanding access to treatments is fundamental to preventing patients from being trapped between high pharmaceutical costs and the danger of irregular products.
A case of food poisoning has occurred in the Saharsa district of Bihar state. More than one hundred people felt unwell after eating prasad prepared during the Satyanarayan worship in Sardikha village, in the Madhya Tola area of Simri Bakhtiyarpur.
The sick include women, men, and children. The mass illness caused panic throughout the village. According to available information, a worship of the god Satyanarayan was held in the village on Thursday evening, after which residents consumed the prasad. Villagers claim that the deterioration of health began gradually the next day.
Initially, some people experienced discomfort, but soon many started complaining of vomiting and diarrhea. While villagers tried to understand what was happening, dozens of people suddenly fell ill in the area. Due to constant vomiting and diarrhea, the condition of many people began to worsen.
After it became known about the large number of cases, anxiety increased among the residents, and they notified the local health department. A medical team was dispatched to the village.
Local residents reported the situation to a medical worker at the Simri Bakhtiyarpur district hospital. Upon receiving the report, the medical team arrived in the village and began treating the victims in Madhya Tola, Sardikha.
The medical team is visiting homes, examining, and treating patients. Special attention is being paid to the condition of those whose health has deteriorated the most. Some villagers are also seeking treatment outside the village.
The health department team is monitoring the entire situation following the mass illness. Currently, the main complaint among the population is vomiting and diarrhea. Residents link the health deterioration to consuming the prasad during the worship.
This incident did not affect any single age group; a large number of villagers, including women, men, and children, fell ill. According to the villagers, many who consumed the prasad began experiencing health problems the very next day.
An atmosphere of fear descended upon the village after news of the disease spread. Residents exchanged information about each other's health. The arrival of the medical team brought relief to the affected families, and medical workers continue to provide assistance to the patients.
Currently, the health department team is in the village, observing the development of the situation. An investigation into the cause of the sudden illness of a large number of people is underway. According to the villagers, the deterioration of health began specifically after consuming the prasad during the worship.
