The World Health Organization (WHO) has released new global guidelines stating that up to 45% of dementia cases can be prevented or slowed down by eliminating several risk factors. These factors include high blood pressure, diabetes, smoking, insufficient physical activity, and, for the first time, air pollution.
Recommendations for Dementia Prevention
The updated guidelines, which represent the first major revision since 2019, reflect a growing scientific understanding that lifestyle, management of chronic diseases, and environmental exposure can significantly affect brain health. The inclusion of air pollution is an important addition to the WHO's guidance on dementia prevention, as evidence accumulates linking prolonged exposure to polluted air with reduced cognitive function.
Characteristics of Dementia
Dementia is a progressive brain disorder that impairs memory, thinking, and the ability to perform daily tasks. Alzheimer's disease accounts for approximately 60–70% of all dementia cases. Although there is currently no cure for this disease, the WHO asserts that a significant portion of the risk can be reduced through a healthier lifestyle and improved management of chronic illnesses.
Situation in India and Global Data
These recommendations are particularly relevant for India, where the burden of dementia is expected to rise as the population ages. A national study published in the peer-reviewed journal Alzheimer's & Dementia showed that about 8.8 million Indians aged 60 and over suffer from dementia, based on a prevalence of 7.4% among the elderly. The WHO's guidance on air pollution is supported by a growing body of data. The 2024 Lancet Commission on Dementia Prevention, Intervention, and Treatment identified air pollution as one of 14 modifiable risk factors that, combined, could account for up to 45% of dementia cases. Furthermore, a 2024 study in BMJ Public Health found both external and internal air pollution to be significant risk factors for dementia in the Indian population.
Global Burden and WHO Advice
Globally, over 57 million people live with dementia, and nearly 10 million new cases are diagnosed annually. Recommendations include regular physical activity, quitting tobacco, limiting alcohol consumption, maintaining a healthy diet, staying socially active and cognitively stimulated, and effectively managing high blood pressure, diabetes, and high cholesterol. Using hearing aids may also help reduce dementia risk if clinically indicated.
WHO Director-General Dr. Tedros Adhanom Ghebreyesus stated: 'Today we know more about what causes dementia risk than ever before, and these guidelines translate that knowledge into practical action.' He added that countries now have clear, evidence-based recommendations that can be immediately applied to protect people's cognitive health.
Caveats and Economic Impact
WHO also cautions against the routine use of Vitamin B or E, omega-3 fatty acids, or multivitamin-mineral supplements to prevent dementia in individuals without a diagnosed deficiency, citing insufficient evidence of benefit. Dementia also creates a significant economic burden: WHO estimates that the disease costs the global economy approximately $1.3 trillion annually, with about half of that burden borne by family and friends in the form of unpaid care.


