A new study was conducted to answer the question of when the best time to practice intermittent fasting is. The research investigated whether concentrating meals at the beginning of the day provides superior results compared to eating later.
The findings indicate that, at least regarding the maintenance of weight loss, the feeding window period may not be as decisive as the ability to integrate certain dietary habits.
Entrance exams for higher and vocational educational institutions for the 2026/2027 academic year were held in the Bukhara region, with all conditions organized at a high level.
To guarantee openness, transparency, and fairness in conducting the exams, all buildings where the tests were held were fully equipped with modern video surveillance cameras. Furthermore, an online monitoring mechanism was created via the website test2026.uz, which contributes to strengthening public control and ensuring process transparency.
The work on organizing and managing the testing procedures was carried out by qualified specialists from the Agency for Assessment of Knowledge and Competencies. Additionally, 114 members of the group supervision, selected through a competition and signing contracts with the agency, as well as 4 translators ensured the exams were conducted in the established manner. The involvement of translators helps create equal opportunities for applicants with disabilities.
Coordination work is being conducted by the working group of the Bukhara Region Hokimiyat to ensure the exams are held in accordance with established procedures and safety requirements. Also, internal affairs bodies, the National Guard, the Emergency Situations Service, and ambulance crews are constantly working to maintain public order and ensure the safety of participants.
The fair, transparent, and honest conduct of entrance exams to higher and vocational educational institutions is of great importance for determining the future educational trajectory of every young person based on their knowledge.
A study presented at the International Alzheimer's Association Conference demonstrated that the combination of THC and CBD, in a specific medical formulation, managed to reduce agitation in individuals with advanced dementia. This research evaluated a medication distinct from commercially available cannabis derivatives.
The clinical trial named Life’s end Benefits of cannaBidiol and tetrahYdrocannabinol (LiBBY) involved 120 participants diagnosed with Alzheimer's or other forms of dementia who were eligible for palliative care. The study followed a rigorous protocol, being multicenter, randomized, double-blind, and placebo-controlled.
Participants received an oral suspension containing THC and CBD or a placebo, without patients, caregivers, or doctors knowing which group they belonged to. Key findings included a drop of 6.27 points in agitation indices after the first two weeks in the THC/CBD treated group, with this improvement maintained throughout the 12 weeks of treatment.
The data showed that 87.2% of participants who received the treatment showed overall improvement, in contrast to only 23.6% in the placebo group. Furthermore, the occurrence of adverse events was similar between both groups. Researchers considered these results extremely notable, demonstrating an unprecedented level of response in clinical trials focused on dementia.
Agitation is cited as a particularly difficult symptom to manage in people with advanced dementia, manifesting as restlessness, aggression, repetitive movements, and emotional distress, also impacting family members and caregivers. Conventional medications used for this purpose, such as antipsychotics, benzodiazepines, and opioids, often present limitations and significant side effects.
Symptom assessment was conducted using the Cohen-Mansfield Agitation Inventory, a tool that analyzes 29 behaviors related to the issue. Researchers observed that the benefits appeared quickly and persisted throughout the entire follow-up period. However, despite the positive results, scientists emphasize that the studied treatment should not be confused with THC and CBD products sold on the market.
Brigid Reynolds, co-principal investigator, stated that the medication used in the research was produced, formulated, and administered under strict medical supervision. According to the researchers, products found in dispensaries or online may have significant variations in their composition, concentration, and quality, making any direct comparison with the formulation used in the trial impossible. Although the LiBBY study points to a promising path for an area lacking alternatives, more investigations are necessary before the therapy can be widely adopted in clinical practice.
